The use of reverse transcription-PCR for the diagnosis of X-linked chronic granulomatous disease

The use of reverse transcription-PCR for the diagnosis of X-linked chronic granulomatous disease

Chronic granulomatous disease (CGD) is an inherited disorder of the innate immune system characterized by a defective oxidative burst of phagocytes and subsequent impairment of their microbicidal activity. Mutations in one of the NADPH-oxidase components affect gene expression or function of this sy...

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Bibliographic Details
Main Authors: P. Agudelo-Flórez, J.A. López, J. Redher, M.M.S. Carneiro-Sampaio, B.T. Costa-Carvalho, A.S. Grumach, A. Condino-Neto
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2004-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Superoxide
Phagocytes
Primary immunodeficiency
Respiratory burst
Neutrophils
Human
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000500001

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000500001

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