The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ

Abstract Phenotypic polarization of macrophages is regulated by a milieu of cues in the local tissue microenvironment. Currently, little is known about how the intrinsic regulators modulate proinflammatory (M1) versus prohealing (M2) macrophages activation. Here, it is observed that insulin‐like gro...

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Bibliographic Details
Main Authors: Xia Wang, Yuge Ji, Panpan Feng, Rucheng Liu, Guosheng Li, Junjie Zheng, Yaqiang Xue, Yaxun Wei, Chunyan Ji, Dawei Chen, Jingxin Li
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202100209