Semisynthesis and Inhibitory Effects of Solidagenone Derivatives on TLR-Mediated Inflammatory Responses

A series of nine derivatives (<b>2</b>–<b>10</b>) were prepared from the diterpene solidagenone (<b>1</b>) and their structures were elucidated by means of spectroscopic studies. Their ability to inhibit inflammatory responses elicited in peritoneal macrophages by...

Full description

Bibliographic Details
Main Authors: Irene Cuadrado, Ángel Amesty, Juan Carlos Cedrón, Juan Carlos Oberti, Ana Estévez-Braun, Sonsoles Hortelano, Beatriz de las Heras
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/23/12/3197