The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO2

The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO2

Maintaining constant CO2 and H+ concentrations in the arterial blood is critical for life. The principal mechanism through which this is achieved in mammals is the respiratory chemoreflex whose circuitry is still elusive. A candidate element of this circuitry is the retrotrapezoid nucleus (RTN), a c...

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Bibliographic Details
Main Authors: Pierre-Louis Ruffault, Fabien D'Autréaux, John A Hayes, Marc Nomaksteinsky, Sandra Autran, Tomoyuki Fujiyama, Mikio Hoshino, Martin Hägglund, Ole Kiehn, Jean-François Brunet, Gilles Fortin, Christo Goridis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
hindbrain
respiration
electrophysiology
transcription factor
genetic
Online Access:https://elifesciences.org/articles/07051

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