Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy.

Several myopathies are associated with defects in autophagic and lysosomal degradation of glycogen, but it remains unclear how glycogen is targeted to the lysosome and what significance this process has for muscle cells. We have established a Drosophila melanogaster model to study glycogen autophagy...

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Bibliographic Details
Main Authors: Jonathan Zirin, Joppe Nieuwenhuis, Norbert Perrimon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3825659?pdf=render