Human CD8+CD28− T Suppressor Cells Expanded by IL-15 In Vitro Suppress in an Allospecific and Programmed Cell Death Protein 1-Dependent Manner

Human CD8+CD28− T Suppressor Cells Expanded by IL-15 In Vitro Suppress in an Allospecific and Programmed Cell Death Protein 1-Dependent Manner

CD8+CD28− T suppressor cells (Ts) have been recently documented to play an important role in alloimmunity. Therefore, understanding and optimizing the conditions under which these cells are generated and/or expanded would greatly facilitate further research and potential clinical use. In this study,...

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Bibliographic Details
Main Authors: Fu Feng, Yanjun Liu, Guihuan Liu, Ping Zhu, Manman Zhu, Hua Zhang, Xiao Lu, Jiumin Liu, Xunrong Luo, Yuming Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
CD8+CD28− T cells
IL-15
suppressor cells
allospecific
programmed cell death protein 1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01442/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01442/full

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