Adaptive Evolution of MERS-CoV to Species Variation in DPP4
Summary: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) likely originated in bats and passed to humans through dromedary camels; however, the genetic mechanisms underlying cross-species adaptation remain poorly understood. Variation in the host receptor, dipeptidyl peptidase 4 (DPP4), can b...
Main Authors: | Michael Letko, Kerri Miazgowicz, Rebekah McMinn, Stephanie N. Seifert, Isabel Sola, Luis Enjuanes, Aaron Carmody, Neeltje van Doremalen, Vincent Munster |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-08-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718311483 |
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