Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection
Plasmodium species produce an ortholog of the cytokine macrophage migration inhibitory factor, PMIF, which modulates the host inflammatory response to malaria. Here, the authors show that inhibition of PMIF may have translational benefits for managing malaria infections.
Bibliographic Details
| Main Authors: |
Alvaro Baeza Garcia,
Edwin Siu,
Tiffany Sun,
Valerie Exler,
Luis Brito,
Armin Hekele,
Gib Otten,
Kevin Augustijn,
Chris J. Janse,
Jeffrey B. Ulmer,
Jürgen Bernhagen,
Erol Fikrig,
Andrew Geall,
Richard Bucala |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-05041-7
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