A Four-Component Domino Reaction: An Eco-Compatible and Highly Efficient Construction of 1,8-Naphthyridine Derivatives, Their In Silico Molecular Docking, Drug Likeness, ADME, and Toxicity Studies

A Four-Component Domino Reaction: An Eco-Compatible and Highly Efficient Construction of 1,8-Naphthyridine Derivatives, Their In Silico Molecular Docking, Drug Likeness, ADME, and Toxicity Studies

A multicomponent domino reaction of enaminone, malononitrile, and o-phthalaldehyde has been established, providing direct access to novel highly functionalized pentacyclic cyclopenta [b] indeno [1, 2, 3-de] [1,8] naphthyridine derivatives. The simplicity of execution, readily available substrates, h...

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Bibliographic Details
Main Authors:	Ankita Garg, Aschalew Tadesse, Rajalakshmanan Eswaramoorthy
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2021/5589837

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