Quantitation of isoprostane isomers in human urine from smokers and nonsmokers by LC-MS/MS1

A simple, rapid liquid chromatography-tandem mass spectrometry method was developed to identify and quantitate in human urine the isoprostanes iPF2α-III, 15-epi-iPF2α-III, iPF2α-VI, and 8,12-iso-iPF2α-VI along with the prostaglandin PGF2α and 2,3-dinor-iPF2α-III, a metabolite of iPF2α-III. Assay spe...

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Bibliographic Details
Main Authors: Weiying Yan, Gary D. Byrd, Michael W. Ogden
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425453