Biological and clinical impact of central nervous system hemangioblastomas in Chinese patients with von Hippel-Lindau disease: implications for treatment

Biological and clinical impact of central nervous system hemangioblastomas in Chinese patients with von Hippel-Lindau disease: implications for treatment

Abstract Objective Central nervous system (CNS) hemangioblastomas (HGBs) are the most frequent cause of mortality in patients with von Hippel-Lindau (VHL) genetic syndrome. However, there is a lack of large studies on the clinical features and optimal management of HGBs in Chinese patients. Methods...

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Bibliographic Details
Main Authors: Zhen Liu, Liang Li, Zhiqiang Yi, Hongzhou Duan, Runchun Lu, Chunwei Li, Lei Li, Kan Gong
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
VHL genetic syndrome
Genetic mutation
Hemangioblastoma surgical treatment
Genetic anticipation
Online Access:http://link.springer.com/article/10.1186/s13053-020-00153-y

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