Making Connections: p53 and the Cathepsin Proteases as Co-Regulators of Cancer and Apoptosis

Making Connections: p53 and the Cathepsin Proteases as Co-Regulators of Cancer and Apoptosis

While viewed as the “guardian of the genome”, the importance of the tumor suppressor p53 protein has increasingly gained ever more recognition in modulating additional modes of action related to cell death. Slowly but surely, its importance has evolved from a mutated genetic locus heavily implicated...

Full description

Bibliographic Details
Main Authors: Surinder M Soond, Lyudmila V Savvateeva, Vladimir A Makarov, Neonila V Gorokhovets, Paul A Townsend, Andrey A Zamyatnin
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
p53
cathepsin
cancer
MOMP
apoptosis
lysosomal membrane permeabilization
Online Access:https://www.mdpi.com/2072-6694/12/11/3476

Internet

https://www.mdpi.com/2072-6694/12/11/3476

Similar Items