Brucella cyclic β-1,2-glucan plays a critical role in the induction of splenomegaly in mice.

Brucella, the etiological agent of animal and human brucellosis, is a bacterium with the capacity to modulate the inflammatory response. Cyclic β-1,2-glucan (CβG) is a virulence factor key for the pathogenesis of Brucella as it is involved in the intracellular life cycle of the bacteria. Using compa...

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Bibliographic Details
Main Authors: Mara S Roset, Andrés E Ibañez, Job Alves de Souza Filho, Juan M Spera, Leonardo Minatel, Sergio C Oliveira, Guillermo H Giambartolomei, Juliana Cassataro, Gabriel Briones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4077732?pdf=render