Decreased S100A9 Expression Promoted Rat Airway Smooth Muscle Cell Proliferation by Stimulating ROS Generation and Inhibiting p38 MAPK

Background. Asthma is a disease with a core abnormality in airway smooth muscle function, and the proliferation of airway smooth muscle cells (ASMCs) plays a pivotal role in asthma airway remodeling. Our previous study showed that S100A9 (S100 calcium-binding protein A9; 400 and 800 ng/mL) significa...

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Bibliographic Details
Main Authors: Lei-Miao Yin, Xiao-Jie Han, Ting-Ting Duan, Yu-Dong Xu, Yu Wang, Luis Ulloa, Yong-Qing Yang
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2016/1462563