A combination of herbal compound (SPTC) along with exercise or metformin more efficiently alleviated diabetic complications through down-regulation of stress oxidative pathway upon activating Nrf2-Keap1 axis in AGE rich diet-induced type 2 diabetic mice

A combination of herbal compound (SPTC) along with exercise or metformin more efficiently alleviated diabetic complications through down-regulation of stress oxidative pathway upon activating Nrf2-Keap1 axis in AGE rich diet-induced type 2 diabetic mice

Abstract Background SPTC is a mix of four herbal components (Salvia officinalis, Panax ginseng, Trigonella foenum-graeceum, and Cinnamomum zeylanicum) which might be prevented the development of AGE rich diet-induced diabetic complication and liver injury through activated the nuclear factor erythro...

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Main Authors: Golbarg Rahimi, Salime Heydari, Bahareh Rahimi, Navid Abedpoor, Iman Niktab, Zahra Safaeinejad, Maryam Peymani, Farzad Seyed Forootan, Zahra Derakhshan, Mohammad Hossein Nasr Esfahani, Kamran Ghaedi
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Nutrition & Metabolism
Subjects:
AGE rich diet
Diabetes
Exercise
Herbal drug
Nrf2-keep pathway
Stress oxidative
Online Access:https://doi.org/10.1186/s12986-021-00543-6

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