Effect of body mass index on pharmacokinetics of paclitaxel in patients with early breast cancer

Effect of body mass index on pharmacokinetics of paclitaxel in patients with early breast cancer

ABSTRACT Background Paclitaxel is dosed according to body surface area (BSA) but there is scant information on actual drug exposure in overweight and obese patients. Methods Early breast cancer patients receiving paclitaxel at 175 mg/m2 every 3 weeks, in two BMI groups (normal, 18–24.9 kg/m2 and ove...

Full description

Bibliographic Details
Main Authors: Vikram Gota, Manjunath Nookala, Avinash Bonda, Ashwin Karanam, Bharati Shriyan, Yogesh Kembhavi, Murari Gurjar, Anand Patil, Ashish Singh, Navin Goyal, Sudeep Gupta
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Cancer Medicine
Subjects:
body surface area
breast cancer
paclitaxel
pharmacokinetics
Online Access:https://doi.org/10.1002/cam4.3865

Internet

https://doi.org/10.1002/cam4.3865

Similar Items