Summary: | A patient presented with skin lesions at sites not contiguous with
Crohn's disease of the bowel and with specific histological features of Crohn's
disease occurring two weeks from the onset of bowel symptoms. Currently a
number of nonspecific skin conditions such as erythema nodosum, pyoderma
gangrenosum and erythema multiforme are accepted as being the most common
skin manifestations of Crohn's disease. It is likely, however, that specific lesions
of Crohn's disease in the skin have been underdiagnosed either because of lack
of biopsy or misinterpretation of the histology. Twenty-three cases with specific
Crohn's disease in the skin have been recorded in the past 25 years, since the
condition has been recognized. Sarcoidosis has been a common misdiagnosis.
The literature relating to multicentric Crohn's disease is reviewed and attention
drawn to its protean and masquerading features. An argument is made for the use
of the term 'multicentric' rather than 'metastatic' in relation to cutaneous
Crohn's disease.
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