Soluble PD-1: Predictive, Prognostic, and Therapeutic Value for Cancer Immunotherapy

Soluble PD-1: Predictive, Prognostic, and Therapeutic Value for Cancer Immunotherapy

Programmed death protein 1 (PD-1) interaction with PD-L1 deliver immunosuppressive environment for tumor growth, and its blockade with directed monoclonal antibodies (anti-PD-1/anti-PD-L1) has shown remarkable clinical outcome. Lately, their soluble counterparts, sPD-1 and sPD-L1, have been detected...

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Bibliographic Details
Main Authors: Muhammad Khan, Zhihong Zhao, Sumbal Arooj, Yuxiang Fu, Guixiang Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
soluble programmed cell death protein 1
local gene therapy
cancer vaccination
prediction
prognosis
immune checkpoint blockade
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.587460/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.587460/full

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