Association between a Single Donor TARC/CCL17 Promotor Polymorphism and Obstructive Chronic Lung Allograft Dysfunction after Lung Transplantation

Association between a Single Donor TARC/CCL17 Promotor Polymorphism and Obstructive Chronic Lung Allograft Dysfunction after Lung Transplantation

Lung transplantation (LTx) outcome is hampered by development of chronic rejection, often manifested as the bronchiolitis obliterans syndrome (BOS). Low serum levels of thymus and activation-regulated chemokine (TARC/CCL17), a chemoattractant, measured during the first month post-LTx are predictive...

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Bibliographic Details
Main Authors: Kevin Budding, Jessica van Setten, Eduard A. van de Graaf, Oliver A. van Rossum, Tineke Kardol-Hoefnagel, Erik-Jan D. Oudijk, C. Erik Hack, Henderikus G. Otten
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
lung transplantation
thymus and activation-regulated chemokine
chronic lung allograft dysfunction
bronchiolitis obliterans syndrome
chronic rejection
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01109/full

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