Simvastatin inhibits interferon-γ-induced MHC class II up-regulation in cultured astrocytes
<p>Abstract</p> <p>Based on their potent anti-inflammatory properties and a preliminary clinical trial, statins (HMG-CoA reductase inhibitors) are being studied as possible candidates for multiple sclerosis (MS) therapy. The pathogenesis of MS is unclear. One theory suggests that t...
Main Authors: | Glazenburg Lisa, Chesik Daniel, Wilczak Nadine, Zeinstra Esther, Kroese Frans GM, De Keyser Jacques |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-07-01
|
Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/3/1/16 |
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