Simvastatin inhibits interferon-γ-induced MHC class II up-regulation in cultured astrocytes

<p>Abstract</p> <p>Based on their potent anti-inflammatory properties and a preliminary clinical trial, statins (HMG-CoA reductase inhibitors) are being studied as possible candidates for multiple sclerosis (MS) therapy. The pathogenesis of MS is unclear. One theory suggests that t...

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Bibliographic Details
Main Authors: Glazenburg Lisa, Chesik Daniel, Wilczak Nadine, Zeinstra Esther, Kroese Frans GM, De Keyser Jacques
Format: Article
Language:English
Published: BMC 2006-07-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/3/1/16