QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC

A convenient method for analyzing the content of vitamins A, D3 and E in premixes has been developed (the tests were carried out using the example of the premixes «Mauervit» and «randvitam») using ultra HPLC. The necessary changes of the procedure have been made in comparison with the ones presented...

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Main Authors: A. V. Baklykov, G. A. Artem’ev, S. A. Glavatskikh, D. S. Kopchuk
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/502
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spelling doaj-bddf7a6e1f8242babda346c23843e8642021-07-28T13:06:55ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01048896502QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLCA. V. Baklykov0G. A. Artem’ev1S. A. Glavatskikh2D. S. Kopchuk3I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of SciencesI.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural State Medicinal UniversityI.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural State Medicinal UniversityI.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B.N. YeltsinA convenient method for analyzing the content of vitamins A, D3 and E in premixes has been developed (the tests were carried out using the example of the premixes «Mauervit» and «randvitam») using ultra HPLC. The necessary changes of the procedure have been made in comparison with the ones presented previously in GOST R 50928-96 due to the presence in the premix components hampering analysis (in particular, Tween 80). The developed procedure has been tested in terms of specificity, accuracy and precision. In addition, the possibility of using a simpler procedure for the analysis of vitamins extract, used as raw material for premix production, has been demonstrated.https://www.pharmjournal.ru/jour/article/view/502ultra hplcquantitative analysisvitamins ad3 and e
collection DOAJ
language Russian
format Article
sources DOAJ
author A. V. Baklykov
G. A. Artem’ev
S. A. Glavatskikh
D. S. Kopchuk
spellingShingle A. V. Baklykov
G. A. Artem’ev
S. A. Glavatskikh
D. S. Kopchuk
QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC
Разработка и регистрация лекарственных средств
ultra hplc
quantitative analysis
vitamins a
d3 and e
author_facet A. V. Baklykov
G. A. Artem’ev
S. A. Glavatskikh
D. S. Kopchuk
author_sort A. V. Baklykov
title QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC
title_short QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC
title_full QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC
title_fullStr QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC
title_full_unstemmed QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC
title_sort quantitative determination of vitamins a, d3 and e in premixes «mauervit» and «grandvitam» by ultra hplc
publisher LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
series Разработка и регистрация лекарственных средств
issn 2305-2066
2658-5049
publishDate 2019-01-01
description A convenient method for analyzing the content of vitamins A, D3 and E in premixes has been developed (the tests were carried out using the example of the premixes «Mauervit» and «randvitam») using ultra HPLC. The necessary changes of the procedure have been made in comparison with the ones presented previously in GOST R 50928-96 due to the presence in the premix components hampering analysis (in particular, Tween 80). The developed procedure has been tested in terms of specificity, accuracy and precision. In addition, the possibility of using a simpler procedure for the analysis of vitamins extract, used as raw material for premix production, has been demonstrated.
topic ultra hplc
quantitative analysis
vitamins a
d3 and e
url https://www.pharmjournal.ru/jour/article/view/502
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AT saglavatskikh quantitativedeterminationofvitaminsad3andeinpremixesmauervitandgrandvitambyultrahplc
AT dskopchuk quantitativedeterminationofvitaminsad3andeinpremixesmauervitandgrandvitambyultrahplc
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