QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC
A convenient method for analyzing the content of vitamins A, D3 and E in premixes has been developed (the tests were carried out using the example of the premixes «Mauervit» and «randvitam») using ultra HPLC. The necessary changes of the procedure have been made in comparison with the ones presented...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
|
Series: | Разработка и регистрация лекарственных средств |
Subjects: | |
Online Access: | https://www.pharmjournal.ru/jour/article/view/502 |
id |
doaj-bddf7a6e1f8242babda346c23843e864 |
---|---|
record_format |
Article |
spelling |
doaj-bddf7a6e1f8242babda346c23843e8642021-07-28T13:06:55ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01048896502QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLCA. V. Baklykov0G. A. Artem’ev1S. A. Glavatskikh2D. S. Kopchuk3I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of SciencesI.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural State Medicinal UniversityI.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural State Medicinal UniversityI.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B.N. YeltsinA convenient method for analyzing the content of vitamins A, D3 and E in premixes has been developed (the tests were carried out using the example of the premixes «Mauervit» and «randvitam») using ultra HPLC. The necessary changes of the procedure have been made in comparison with the ones presented previously in GOST R 50928-96 due to the presence in the premix components hampering analysis (in particular, Tween 80). The developed procedure has been tested in terms of specificity, accuracy and precision. In addition, the possibility of using a simpler procedure for the analysis of vitamins extract, used as raw material for premix production, has been demonstrated.https://www.pharmjournal.ru/jour/article/view/502ultra hplcquantitative analysisvitamins ad3 and e |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
A. V. Baklykov G. A. Artem’ev S. A. Glavatskikh D. S. Kopchuk |
spellingShingle |
A. V. Baklykov G. A. Artem’ev S. A. Glavatskikh D. S. Kopchuk QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC Разработка и регистрация лекарственных средств ultra hplc quantitative analysis vitamins a d3 and e |
author_facet |
A. V. Baklykov G. A. Artem’ev S. A. Glavatskikh D. S. Kopchuk |
author_sort |
A. V. Baklykov |
title |
QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC |
title_short |
QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC |
title_full |
QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC |
title_fullStr |
QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC |
title_full_unstemmed |
QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC |
title_sort |
quantitative determination of vitamins a, d3 and e in premixes «mauervit» and «grandvitam» by ultra hplc |
publisher |
LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
series |
Разработка и регистрация лекарственных средств |
issn |
2305-2066 2658-5049 |
publishDate |
2019-01-01 |
description |
A convenient method for analyzing the content of vitamins A, D3 and E in premixes has been developed (the tests were carried out using the example of the premixes «Mauervit» and «randvitam») using ultra HPLC. The necessary changes of the procedure have been made in comparison with the ones presented previously in GOST R 50928-96 due to the presence in the premix components hampering analysis (in particular, Tween 80). The developed procedure has been tested in terms of specificity, accuracy and precision. In addition, the possibility of using a simpler procedure for the analysis of vitamins extract, used as raw material for premix production, has been demonstrated. |
topic |
ultra hplc quantitative analysis vitamins a d3 and e |
url |
https://www.pharmjournal.ru/jour/article/view/502 |
work_keys_str_mv |
AT avbaklykov quantitativedeterminationofvitaminsad3andeinpremixesmauervitandgrandvitambyultrahplc AT gaartemev quantitativedeterminationofvitaminsad3andeinpremixesmauervitandgrandvitambyultrahplc AT saglavatskikh quantitativedeterminationofvitaminsad3andeinpremixesmauervitandgrandvitambyultrahplc AT dskopchuk quantitativedeterminationofvitaminsad3andeinpremixesmauervitandgrandvitambyultrahplc |
_version_ |
1721276781279838208 |