A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging

Introduction. Abdominal adhesions can cause serious morbidity and complicate subsequent operations. Their diagnosis is often one of exclusion due to a lack of a reliable, non-invasive diagnostic technique. Development and testing of a candidate technique are described below. Method. During respirati...

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Main Authors: David Randall, John Fenner, Richard Gillott, Richard ten Broek, Chema Strik, Paul Spencer, Karna Dev Bardhan
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/2523768
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spelling doaj-bdcce0d4d2244d17b4747e7bb03311a92020-11-24T23:46:03ZengHindawi LimitedGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/25237682523768A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance ImagingDavid Randall0John Fenner1Richard Gillott2Richard ten Broek3Chema Strik4Paul Spencer5Karna Dev Bardhan6Medical Physics Group, Department of Cardiovascular Science, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UKMedical Physics Group, Department of Cardiovascular Science, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UKThe Rotherham NHS Foundation Trust, Rotherham Hospital, Moorgate Road, Rotherham S60 2UD, UKRadboud University Medical Centre, Department of Surgery, P.O. Box 9101, 6500 HB Nijmegen, NetherlandsRadboud University Medical Centre, Department of Surgery, P.O. Box 9101, 6500 HB Nijmegen, NetherlandsThe Rotherham NHS Foundation Trust, Rotherham Hospital, Moorgate Road, Rotherham S60 2UD, UKThe Rotherham NHS Foundation Trust, Rotherham Hospital, Moorgate Road, Rotherham S60 2UD, UKIntroduction. Abdominal adhesions can cause serious morbidity and complicate subsequent operations. Their diagnosis is often one of exclusion due to a lack of a reliable, non-invasive diagnostic technique. Development and testing of a candidate technique are described below. Method. During respiration, smooth visceral sliding motion occurs between the abdominal contents and the walls of the abdominal cavity. We describe a technique involving image segmentation and registration to calculate shear as an analogue for visceral slide based on the tracking of structures throughout the respiratory cycle. The presence of an adhesion is attributed to a resistance to visceral slide resulting in a discernible reduction in shear. The abdominal movement due to respiration is captured in sagittal dynamic MR images. Results. Clinical images were selected for analysis, including a patient with a surgically confirmed adhesion. Discernible reduction in shear was observed at the location of the adhesion while a consistent, gradually changing shear was observed in the healthy volunteers. Conclusion. The technique and its validation show encouraging results for adhesion detection but a larger study is now required to confirm its potential.http://dx.doi.org/10.1155/2016/2523768
collection DOAJ
language English
format Article
sources DOAJ
author David Randall
John Fenner
Richard Gillott
Richard ten Broek
Chema Strik
Paul Spencer
Karna Dev Bardhan
spellingShingle David Randall
John Fenner
Richard Gillott
Richard ten Broek
Chema Strik
Paul Spencer
Karna Dev Bardhan
A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
Gastroenterology Research and Practice
author_facet David Randall
John Fenner
Richard Gillott
Richard ten Broek
Chema Strik
Paul Spencer
Karna Dev Bardhan
author_sort David Randall
title A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_short A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_full A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_fullStr A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_full_unstemmed A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_sort novel diagnostic aid for detection of intra-abdominal adhesions to the anterior abdominal wall using dynamic magnetic resonance imaging
publisher Hindawi Limited
series Gastroenterology Research and Practice
issn 1687-6121
1687-630X
publishDate 2016-01-01
description Introduction. Abdominal adhesions can cause serious morbidity and complicate subsequent operations. Their diagnosis is often one of exclusion due to a lack of a reliable, non-invasive diagnostic technique. Development and testing of a candidate technique are described below. Method. During respiration, smooth visceral sliding motion occurs between the abdominal contents and the walls of the abdominal cavity. We describe a technique involving image segmentation and registration to calculate shear as an analogue for visceral slide based on the tracking of structures throughout the respiratory cycle. The presence of an adhesion is attributed to a resistance to visceral slide resulting in a discernible reduction in shear. The abdominal movement due to respiration is captured in sagittal dynamic MR images. Results. Clinical images were selected for analysis, including a patient with a surgically confirmed adhesion. Discernible reduction in shear was observed at the location of the adhesion while a consistent, gradually changing shear was observed in the healthy volunteers. Conclusion. The technique and its validation show encouraging results for adhesion detection but a larger study is now required to confirm its potential.
url http://dx.doi.org/10.1155/2016/2523768
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