Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer

Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer

Bladder cancer (BC), a heterogeneous disease characterized by high recurrence rates, is diagnosed and monitored by cystoscopy. Accurate clinical staging based on biopsy remains a challenge, and additional, objective diagnostic tools are needed urgently. We used exosomal DNA (exoDNA) as an analyte to...

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Bibliographic Details
Main Authors: Xunian Zhou, Paul Kurywchak, Kerri Wolf-Dennen, Sara P.Y. Che, Dinanath Sulakhe, Mark D’Souza, Bingqing Xie, Natalia Maltsev, T. Conrad Gilliam, Chia-Chin Wu, Kathleen M. McAndrews, Valerie S. LeBleu, David J. McConkey, Olga V. Volpert, Shanna M. Pretzsch, Bogdan A. Czerniak, Colin P. Dinney, Raghu Kalluri
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
bladder cancer
biomarker
cancer
exosomes
extracellular vesicles
size exclusion chromatography
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050121000942

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http://www.sciencedirect.com/science/article/pii/S2329050121000942

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