The mechanism of BMI1 in regulating cancer stemness maintenance, metastasis, chemo- and radiation resistance

BMI1 is involved in the occurrence and development of many types of cancer through a variety of signaling pathways. BMI1, which is overexpressed in cancer, is often associated with chemo- and radiation resistance and poor prognosis in cancer patients. This article reviews the current understanding o...

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Bibliographic Details
Main Authors: Xiaoshan Xu, Zhen Wang, Nan Liu, Pengxing Zhang, Hui Liu, Jing Qi, Yanyang Tu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Cancer Translational Medicine
Subjects:
Online Access:http://www.cancertm.com/article.asp?issn=2395-3977;year=2018;volume=4;issue=2;spage=59;epage=63;aulast=Xu