Overexpression of miR-146a Might Regulate Polarization Transitions of BV-2 Cells Induced by High Glucose and Glucose Fluctuations

Overexpression of miR-146a Might Regulate Polarization Transitions of BV-2 Cells Induced by High Glucose and Glucose Fluctuations

Microglia are critical in neuroinflammation. M1/M2 polarization transitions of microglial phenotypes determine the states of neuroinflammation and are regulated by multiple pathways, including miRNAs and other epigenetic regulations. This study investigated the polarization transitions of microglia...

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Bibliographic Details
Main Authors: Yinqiong Huang, Zhenling Liao, Xiahong Lin, Xiaohong Wu, Xiaoyu Chen, Xuefeng Bai, Yong Zhuang, Yingxia Yang, Jinying Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Endocrinology
Subjects:
microglia
polarization transitions
miR-146a
neuroinflammation
glucose fluctuation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00719/full

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