The effect of single dose of thymoquinone, the main constituents of Nigella sativa, in guinea pig model of asthma

The effect of single dose of thymoquinone, the main constituents of Nigella sativa, in guinea pig model of asthma

Introduction: In previous studies, the relaxant and antihistaminic effects of thymoquinone, the main constituents of Nigella sativa, have been demonstrated on guinea pig tracheal chains. In the present study, the prophylactic effect of (IP) single dose of thymoquinone on tracheal responsiveness and...

Full description

Bibliographic Details
Main Authors:	Keyhanmanesh Rana, Pejman Laleh, Omrani Hasan, Mirzamohammadi Zahra, Shahbazfar Amir A
Format:	Article
Language:	English
Published:	Tabriz University of Medical Sciences 2014-06-01
Series:	BioImpacts
Subjects:	Asthma Thymoquinone Inflammation Tracheal responsiveness
Online Access:	http://journals.tbzmed.ac.ir/BI/PDF/BI-4-75.pdf

Similar Items

Thymoquinone, the main constituent of Nigella sativa, affects adenosine receptors in asthmatic guinea pigs
by: Laleh Pejman, et al.
Published: (2015-12-01)

Gastrointestinal effects of Nigella sativa and its main constituent, thymoquinone: a review
by: Farzaneh Shakeri, et al.
Published: (2016-01-01)

Skeletal Muscle Relaxant Effects of Thymoquinone, the Major Constituent of Nigella sativa
by: S Parvardeh, et al.
Published: (2015-05-01)

Inhibitory Effects of Thymoquinone, the Major Component of Nigella sativa L. Seeds, on Spontaneous and Evoked Contractions of Guinea Pig Isolated Ileum
by: S Parvardeh, et al.
Published: (2007-09-01)

Study on the anticonvulsant activity of thymoquinone, the major constituent of Nigella sativa L. seeds, through intracerebroventricular injection
by: S Parvardeh, et al.
Published: (2005-05-01)

Review on Clinical Trials of Black Seed (Nigella sativa ) and Its Active Constituent, Thymoquinone
by: Alireza Tavakkoli, et al.
Published: (2017-09-01)

Black cumin (Nigella sativa) and its constituent (thymoquinone): a review on antimicrobial effects
by: Fatemeh Forouzanfar, et al.
Published: (2015-12-01)

The effect of Nigella sativa extract on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs
by: Mohammad Hossein Boskabady, et al.
Published: (2011-01-01)

Dissecting the Potential Roles of Nigella sativa and Its Constituent Thymoquinone on the Prevention and on the Progression of Alzheimer's Disease
by: Marco Cascella, et al.
Published: (2018-02-01)

Role of Nigella sativa and Its Constituent Thymoquinone on Chemotherapy-Induced Nephrotoxicity: Evidences from Experimental Animal Studies
by: Marco Cascella, et al.
Published: (2017-06-01)

Protective effect of thymoquinone, the active constituent of Nigella sativa fixed oil, against ethanol toxicity in rats
by: Sayed Masoud Hosseini, et al.
Published: (2017-08-01)

The Relaxant Effects of Different Methanolic Fractions of Nigella sativa on Guinea Pig Tracheal Chains
by: Rana Keyhanmanesh, et al.
Published: (2013-02-01)

A review on the hypoglycemic effect of nigella sativa and thymoquinone
by: Abdullah O Bamosa
Published: (2015-01-01)

The Main Relaxant Constituents of Nigella Sativa Methanolic Fraction on Guinea Pig Tracheal Chains
by: Rana Keyhanmanesh, et al.
Published: (2013-06-01)

Protective Effects of Black Cumin (<i>Nigella sativa</i>) and Its Bioactive Constituent, Thymoquinone against Kidney Injury: An Aspect on Pharmacological Insights
by: Md. Abdul Hannan, et al.
Published: (2021-08-01)

Review of Pharmacological and Toxicological Effects of Nigella sativa and Its Active Constituents
by: T Ziaee, et al.
Published: (2012-05-01)

<i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal Therapy
by: Mohamed Mekhemar, et al.
Published: (2020-12-01)

Effects of Nigella sativa oil and thymoquinone on radiation-induced oxidative stress in kidney tissue of rats
by: Hilal Alkis, et al.
Published: (2021-07-01)

The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications
by: Rana Keyhanmanesh, et al.
Published: (2015-12-01)

Hypnotic and muscle relaxant activity of thymoquinone, the major active constituent of Nigella sativa seeds, and its effects on locomotor activity and motor coordination in mice
by: S Parvardeh, et al.
Published: (2003-12-01)

The effects of Nigella sativa hydro-alcoholic extract and thymoquinone on lipopolysaccharide - induced depression like behavior in rats
by: Mahmoud Hosseini, et al.
Published: (2012-01-01)

Thymoquinone: From Nigella sativa to a protective pharmacological compound in managing opioid dependence and amphetamine type stimulant issues
by: Liyana Hazwani Mohd Adnan, et al.
Published: (2020-07-01)

The Effect of Adenosine A2A and A2B Antagonists on Tracheal Responsiveness, Serum Levels of Cytokines and Lung Inflammation in Guinea Pig Model of Asthma
by: Laleh Pejman, et al.
Published: (2014-03-01)

Thymoquinone, the Most Prominent Constituent of Nigella Sativa, Attenuates Liver Damage in Streptozotocin-Induced Diabetic Rats via Regulation of Oxidative Stress, Inflammation and Cyclooxygenase-2 Protein Expression
by: Saleh A. Almatroodi, et al.
Published: (2021-04-01)

Alteration in Thymoquinone Content of Nigella sativa Seeds After Processing by a Traditional Method and Stability Assessment of Raw and Processed Seeds
by: Homa Hajimehdipoor, et al.
Published: (2018-09-01)

Protective effect of Nigella sativa and thymoquinone on serum/glucose deprivation-induced DNA damage in PC12 cells
by: Beheshteh Babazadeh, et al.
Published: (2012-06-01)

Protective effect of Nigella sativa and thymoquinone on serum/glucose deprivation-induced DNA damage in PC12 cells
by: Beheshteh Babazadeh, et al.
Published: (2012-06-01)

Neuropharmacological effects of Nigella sativa
by: Farimah Beheshti, et al.
Published: (2016-01-01)

Clinical and experimental effects of Nigella sativa and its constituents on respiratory and allergic disorders
by: Zahra Gholamnezhad, et al.
Published: (2019-04-01)

Effect of Alpha-Hederin, the active constituent of Nigella sativa, on miRNA-126, IL-13 mRNA levels and inflammation of lungs in ovalbumin-sensitized male rats
by: Maryam Fallahi, et al.
Published: (2016-01-01)

<i>Nigella sativa</i> and Its Active Compound, Thymoquinone, Accelerate Wound Healing in an In Vivo Animal Model: A Comprehensive Review
by: Nusaibah Sallehuddin, et al.
Published: (2020-06-01)

Thymoquinone Prevents Myocardial and Perivascular Fibrosis Induced by Chronic Lipopolysaccharide Exposure in Male Rats - Thymoquinone and Cardiac Fibrosis -
by: Fereshteh Asgharzadeh, et al.
Published: (2018-12-01)

Effect of Thymoquinone on Reproductive Parameter in Morphine-treated Male Mice
by: Mohammad Reza Salahshoor, et al.
Published: (2018-01-01)

Protective Effects of Thymoquinone, an Active Compound of <i>Nigella sativa</i>, on Rats with <i>Benzo(a)pyrene</i>-Induced Lung Injury through Regulation of Oxidative Stress and Inflammation
by: Mohammad A. Alzohairy, et al.
Published: (2021-05-01)

Effects of thymoquinone rich fraction and thymoquinone on plasma lipoprotein levels and hepatic low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes expression
by: Ghanya Al-Naqeep, et al.
Published: (2009-07-01)

The protective effect of Nigella sativa against liver injury: a review
by: Hamid Mollazadeh, et al.
Published: (2015-12-01)

Renal injury, nephrolithiasis and Nigella sativa: A mini review
by: Parichehr Hayatdavoudi, et al.
Published: (2016-01-01)

Nigella sativa and its Derivatives as Food Toxicity Protectant Agents
by: Zahra Karimi, et al.
Published: (2019-02-01)

Antidotal effects of thymoquinone against neurotoxic agents
by: Sanati Ali Rajabpour, et al.
Published: (2018-08-01)

The effects of thymoquinone against morphine-induced damages on male mice liver
by: Mohammad Reza Salahshoor, et al.
Published: (2018-01-01)