A Computational Approach for Understanding the Interactions between Graphene Oxide and Nucleoside Diphosphate Kinase with Implications for Heart Failure

A Computational Approach for Understanding the Interactions between Graphene Oxide and Nucleoside Diphosphate Kinase with Implications for Heart Failure

During a heart failure, an increased content and activity of nucleoside diphosphate kinase (NDPK) in the sarcolemmal membrane is responsible for suppressing the formation of the second messenger cyclic adenosine monophosphate (cAMP)—a key component required for calcium ion homeostasis for the proper...

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Bibliographic Details
Main Authors: Anushka Ray, Isaac Macwan, Shrishti Singh, Sushila Silwal, Prabir Patra
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Nanomaterials
Subjects:
nucleoside diphosphate kinase
graphene oxide
molecular dynamics
heart failure
Online Access:http://www.mdpi.com/2079-4991/8/2/57

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