Evidence for limited genetic compartmentalization of HIV-1 between lung and blood.

Evidence for limited genetic compartmentalization of HIV-1 between lung and blood.

BACKGROUND:HIV-1 is frequently detected in the lungs of infected individuals and is likely important in the development of pulmonary opportunistic infections. The unique environment of the lung, rich in alveolar macrophages and with specialized local immune responses, may contribute to differential...

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Bibliographic Details
Main Authors: Laura Heath, Alan Fox, Jan McClure, Kurt Diem, Angélique B van 't Wout, Hong Zhao, David R Park, Jeffrey T Schouten, Homer L Twigg, Lawrence Corey, James I Mullins, John E Mittler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2736399?pdf=render

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