Engineering a Human Plasmacytoid Dendritic Cell-Based Vaccine to Prime and Expand Multispecific Viral and Tumor Antigen-Specific T-Cells

Engineering a Human Plasmacytoid Dendritic Cell-Based Vaccine to Prime and Expand Multispecific Viral and Tumor Antigen-Specific T-Cells

Because dendritic cells are crucial to prime and expand antigen-specific CD8<sup>+</sup> T-cells, several strategies are designed to use them in therapeutic vaccines against infectious diseases or cancer. In this context, off-the-shelf allogeneic dendritic cell-based platforms are more a...

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Bibliographic Details
Main Authors: Kevin Lenogue, Alexandre Walencik, Karine Laulagnier, Jean-Paul Molens, Houssem Benlalam, Brigitte Dreno, Pierre Coulie, Martin Pule, Laurence Chaperot, Joël Plumas
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Vaccines
Subjects:
plasmacytoid dendritic cells
vaccination
immunotherapy
infectious diseases
cancer diseases
Online Access:https://www.mdpi.com/2076-393X/9/2/141

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