Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
Objective: The aim of this study was to investigate the existence of human T-lymphotropic virus type 1 (HTLV-1) in subgingival plaque of HTLV-1 seropositive pa-tients. Materials and Methods: A total of 18 patients including 13 females and fivemales, with a mean age of 37 years participated in thi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2008-09-01
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| Series: | Frontiers in Dentistry |
| Subjects: | |
| Online Access: | https://jdt.tums.ac.ir/index.php/jdt/article/view/157 |
| Summary: | Objective: The aim of this study was to investigate the existence of human T-lymphotropic virus type 1 (HTLV-1) in subgingival plaque of HTLV-1 seropositive pa-tients.
Materials and Methods: A total of 18 patients including 13 females and fivemales, with a mean age of 37 years participated in this descriptive study. Half of them were HTLV-1 carriers and the others were in HTLV-1 associated myelopathy tropical spastic paraparesia (HAM/TSP) stage.Subgingival dental plaque samples were taken using sterile paper points and examined to detect HTLV-1 using polymerase chain reaction (PCR).
Results: None of the carrier stage patients revealed HTLV-1 virus, while only one patient in the HAM/TSP group was found with the virus.
Conclusion: This study showed that the existence of HTLV-1 virus in subgingival plaque of patients suffering from HTLV-1 in carrier and HAM/TSP stages with healthy periodon-tium is rare. Studies with larger samples are recommended.
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| ISSN: | 2676-296X |