Electrochemical Detection of Prostate Cancer Biomarker PCA3 Using Specific RNA-Based Aptamer Labelled with Ferrocene

Electrochemical Detection of Prostate Cancer Biomarker PCA3 Using Specific RNA-Based Aptamer Labelled with Ferrocene

This paper reports on a feasibility study of electrochemical in-vitro detection of prostate cancer biomarker PCA3 (prostate cancer antigen 3) in direct assay with specific RNA aptamer labelled with a redox group (ferrocene) and immobilized on a screen-printed gold electrode surface. The cyclic volta...

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Bibliographic Details
Main Authors: Alexei Nabok, Hisham Abu-Ali, Sarra Takita, David P. Smith
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Chemosensors
Subjects:
prostate cancer
RNA transcript PCA3
aptamer
electrochemical biosensor
cyclic voltammograms
impedance spectroscopy
Online Access:https://www.mdpi.com/2227-9040/9/4/59

Internet

https://www.mdpi.com/2227-9040/9/4/59

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