The Effect Of Arbutin On The Expression Of Tumor Suppressor P53, BAX/BCL-2 Ratio And Oxidative Stress Induced By Tert-Butyl Hydroperoxide In Fibroblast And LNcap Cell Lines

The Effect Of Arbutin On The Expression Of Tumor Suppressor P53, BAX/BCL-2 Ratio And Oxidative Stress Induced By Tert-Butyl Hydroperoxide In Fibroblast And LNcap Cell Lines

Objective: Arbutin (p-hydroxyphenyl-β-D-glucopyranoside) possesses beneficial functions including antioxidant, antiinflammatory, and anti-tumoral activities. Due to the important role of oxidative stress and apoptosis in the successful treatment of cancer, understanding mechanisms that lead to apo...

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Bibliographic Details
Main Authors: Shima Ebadollahi, Mahdi Pouramir, Ebrahim Zabihi, Monireh Golpour, Mohsen Aghajanpour-Mir
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2021-01-01
Series:Cell Journal
Subjects:
arbutin
fibroblast
lncap
oxidative stress
tert-butyl hydroperoxide
Online Access:https://celljournal.org/journal/article/fulltext/the-effect-of-arbutin-on-expression-of-tumor-suppressor-p53-bax-bcl-2-ratio-and-oxidative-stress-induced-by-tert-butyl-hydroperoxide-in-fibroblast-and-lncap-cell-lines.pdf

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https://celljournal.org/journal/article/fulltext/the-effect-of-arbutin-on-expression-of-tumor-suppressor-p53-bax-bcl-2-ratio-and-oxidative-stress-induced-by-tert-butyl-hydroperoxide-in-fibroblast-and-lncap-cell-lines.pdf

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