Proteomic Analysis of Gossypol Induces Necrosis in Multiple Myeloma Cells

Gossypol is a phenolic aldehyde extracted from plants and is known to be an antitumor agent to induce cancer cell apoptosis. In the present study, multiple myeloma cells were treated with gossypol, which resulted in an increase of cellular reactive oxygen species (ROS) and cell necrosis. Quantitativ...

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Bibliographic Details
Main Authors: Renhua Xu, Enbing Tian, Haiping Tang, Chongdong Liu, Qingtao Wang
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/839232