Virus-Like Particles Derived From a Virulent Strain of Pest des Petits Ruminants Virus Elicit a More Vigorous Immune Response in Mice and Small Ruminants Than Those From a Vaccine Strain

Virus-Like Particles Derived From a Virulent Strain of Pest des Petits Ruminants Virus Elicit a More Vigorous Immune Response in Mice and Small Ruminants Than Those From a Vaccine Strain

Peste des petits ruminants (PPRs) is highly contagious, acute or subacute disease of small ruminants caused by peste des petits ruminants virus (PPRV). To date, several studies have designed and evaluated PPRV-like particles (VLPs) as a vaccine candidate for the prevention and control of PPR, with t...

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Bibliographic Details
Main Authors: Feihu Yan, Entao Li, Ling Li, Zachary Schiffman, Pei Huang, Shengnan Zhang, Guohua Li, Hongli Jin, Hualei Wang, Xinghai Zhang, Yuwei Gao, Na Feng, Yongkun Zhao, Chengyu Wang, Xianzhu Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Microbiology
Subjects:
peste des petits ruminants virus
virus-like particles
small ruminants
virulent strain
vaccine strain
immune response
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00609/full

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