Assessing performance of orthology detection strategies applied to eukaryotic genomes.

Orthology detection is critically important for accurate functional annotation, and has been widely used to facilitate studies on comparative and evolutionary genomics. Although various methods are now available, there has been no comprehensive analysis of performance, due to the lack of a genomic-s...

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Bibliographic Details
Main Authors: Feng Chen, Aaron J Mackey, Jeroen K Vermunt, David S Roos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0000383