Generation of a miR-26b stem-loop knockout human iPSC line, MCRIi019-A-1, using CRISPR/Cas9 editing
miR-26b has been implicated in a wide range of human diseases, including cancer, diabetes, heart disease, Alzheimer’s disease and osteoarthritis. To provide a tool to explore the importance of miR-26b in this broad context, we have generated and characterized a homozygous miR-26b stem-loop knockout...
Main Authors: | Louise H.W. Kung, Lisa Sampurno, Christopher B. Little, Shireen R. Lamandé, John F. Bateman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506120304190 |
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