Synthesis, docking and in-vitro screening of mannich bases of thiosemicarbazide for anti-fungal activity

Mannich bases and thiosemicarbazide individually show antimicrobial, antifungal, anticonvulsant, antimalarial, analgesic and anti-inflammatory type of varied pharmacological activities. The novelty of the present work is the synthesis of mannich bases of thiosemicarbazide as mutual prodrugs. In step...

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Bibliographic Details
Main Authors: Sachin A. Pishawikar, Harinath N. More
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535213003560