Quantitating the Transfer of the HTLV-1 p8 Protein Between T-Cells by Flow Cytometry

Quantitating the Transfer of the HTLV-1 p8 Protein Between T-Cells by Flow Cytometry

The Human T-cell leukemia virus type 1 (HTLV-1)-encoded accessory protein p8 is cleaved from the precursor protein p12 encoded by the HTLV-1 open reading frame I. Both p12 and p8 are thought to contribute to efficient viral persistence. Mechanistically, p8 induces T-cell conjugates and cellular cond...

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Bibliographic Details
Main Authors: Norbert Donhauser, Stefanie Heym, Andrea K. Thoma-Kress
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Microbiology
Subjects:
HTLV-1
p8
virus transmission
protein transport
flow cytometry
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00400/full

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