Epigenetics and diabetes mellitus

Epigenetic mechanisms were shown to be involved in the control of endocrine cell fate decision, islet differentiation, β-cell identity, proliferation, and mature function. The pathologic mechanisms involved in the development of type 1 diabetes may include DNA methylation, histone modification, micr...

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Main Author: Mohammed K Rehan
Format: Article
Language:English
Published: SpringerOpen 2016-01-01
Series:The Egyptian Journal of Internal Medicine
Subjects:
Online Access:http://www.esim.eg.net/article.asp?issn=1110-7782;year=2016;volume=28;issue=2;spage=39;epage=51;aulast=Rehan
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spelling doaj-bd54cc242b664f25b48638f809eb00002020-11-25T04:00:46ZengSpringerOpenThe Egyptian Journal of Internal Medicine1110-77822090-90982016-01-01282395110.4103/1110-7782.193890Epigenetics and diabetes mellitusMohammed K RehanEpigenetic mechanisms were shown to be involved in the control of endocrine cell fate decision, islet differentiation, β-cell identity, proliferation, and mature function. The pathologic mechanisms involved in the development of type 1 diabetes may include DNA methylation, histone modification, microRNA, and molecular mimicry. These mechanisms may act through the regulation of gene expression.http://www.esim.eg.net/article.asp?issn=1110-7782;year=2016;volume=28;issue=2;spage=39;epage=51;aulast=Rehandiabetesepigeneticgene expression
collection DOAJ
language English
format Article
sources DOAJ
author Mohammed K Rehan
spellingShingle Mohammed K Rehan
Epigenetics and diabetes mellitus
The Egyptian Journal of Internal Medicine
diabetes
epigenetic
gene expression
author_facet Mohammed K Rehan
author_sort Mohammed K Rehan
title Epigenetics and diabetes mellitus
title_short Epigenetics and diabetes mellitus
title_full Epigenetics and diabetes mellitus
title_fullStr Epigenetics and diabetes mellitus
title_full_unstemmed Epigenetics and diabetes mellitus
title_sort epigenetics and diabetes mellitus
publisher SpringerOpen
series The Egyptian Journal of Internal Medicine
issn 1110-7782
2090-9098
publishDate 2016-01-01
description Epigenetic mechanisms were shown to be involved in the control of endocrine cell fate decision, islet differentiation, β-cell identity, proliferation, and mature function. The pathologic mechanisms involved in the development of type 1 diabetes may include DNA methylation, histone modification, microRNA, and molecular mimicry. These mechanisms may act through the regulation of gene expression.
topic diabetes
epigenetic
gene expression
url http://www.esim.eg.net/article.asp?issn=1110-7782;year=2016;volume=28;issue=2;spage=39;epage=51;aulast=Rehan
work_keys_str_mv AT mohammedkrehan epigeneticsanddiabetesmellitus
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