A functional Variant (Rs35592567) in TP63 at 3q28 is Associated with Gastric Cancer Risk via Modifying its Regulation by MicroRNA-140

A functional Variant (Rs35592567) in TP63 at 3q28 is Associated with Gastric Cancer Risk via Modifying its Regulation by MicroRNA-140

Background/Aims: TP63 was believed to play an important role in the development of many malignancies, while the polymorphisms located at the miRNA binding sites within the 3’UTR of TP63 mRNA may interfere with its expression. In this study, we aimed to study the role of TP63 regulation in the tumori...

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Bibliographic Details
Main Authors: Chaomin Lu, Yongwei Yang, Siyue Ma
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Rs35592567
TP63
Gastric cancer
MiR-140
3’-UTR
Online Access:https://www.karger.com/Article/FullText/489802

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