Pupil fluctuations track rapid changes in adrenergic and cholinergic activity in cortex

In addition to light intensity, changes in pupil diameter are correlated with mental effort, attention and levels of arousal. Reimer et al. report that across behavioural states, fluctuations in pupil diameter are highly correlated with activity of noradrenergic and cholinergic projection neurons.

Bibliographic Details
Main Authors: Jacob Reimer, Matthew J McGinley, Yang Liu, Charles Rodenkirch, Qi Wang, David A McCormick, Andreas S Tolias
Format: Article
Language:English
Published: Nature Publishing Group 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13289

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