Antidepressant and neurocognitive effects of isoflurane anesthesia versus electroconvulsive therapy in refractory depression.

Antidepressant and neurocognitive effects of isoflurane anesthesia versus electroconvulsive therapy in refractory depression.

BACKGROUND:Many patients have serious depression that is nonresponsive to medications, but refuse electroconvulsive therapy (ECT). Early research suggested that isoflurane anesthesia may be an effective alternative to ECT. Subsequent studies altered drug, dose or number of treatments, and failed to...

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Bibliographic Details
Main Authors: Howard R Weeks, Scott C Tadler, Kelly W Smith, Eli Iacob, Mikala Saccoman, Andrea T White, Joshua D Landvatter, Gordon J Chelune, Yana Suchy, Elaine Clark, Michael K Cahalan, Lowry Bushnell, Derek Sakata, Alan R Light, Kathleen C Light
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724904?pdf=render

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