Adaptive Immunity to Dengue Virus: Slippery Slope or Solid Ground for Rational Vaccine Design?

The four serotypes of dengue virus are the most widespread causes of arboviral disease, currently placing half of the human population at risk of infection. Pre-existing immunity to one dengue virus serotype can predispose to severe disease following secondary infection with a different serotype. Th...

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Bibliographic Details
Main Authors: Lucas Wilken, Guus F. Rimmelzwaan
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/6/470