Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion
The authors show that the fungal pathogen Candida albicans exploits diverse host-associated signals, including specific nutrients and stresses, to promote immune evasion by masking cell wall β-glucan, a major pathogen-associated molecular pattern.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2019-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-13298-9 |
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doaj-bd3459245a7f49d29f8307da698409ae |
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Article |
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doaj-bd3459245a7f49d29f8307da698409ae2021-05-11T12:14:49ZengNature Publishing GroupNature Communications2041-17232019-11-0110111410.1038/s41467-019-13298-9Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasionArnab Pradhan0Gabriela M. Avelar1Judith M. Bain2Delma Childers3Chloe Pelletier4Daniel E. Larcombe5Elena Shekhova6Mihai G. Netea7Gordon D. Brown8Lars Erwig9Neil A. R. Gow10Alistair J. P. Brown11Institute of Medical SciencesInstitute of Medical SciencesInstitute of Medical SciencesInstitute of Medical SciencesInstitute of Medical SciencesInstitute of Medical SciencesInstitute of Medical SciencesDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical CenterInstitute of Medical SciencesInstitute of Medical SciencesInstitute of Medical SciencesInstitute of Medical SciencesThe authors show that the fungal pathogen Candida albicans exploits diverse host-associated signals, including specific nutrients and stresses, to promote immune evasion by masking cell wall β-glucan, a major pathogen-associated molecular pattern.https://doi.org/10.1038/s41467-019-13298-9 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Arnab Pradhan Gabriela M. Avelar Judith M. Bain Delma Childers Chloe Pelletier Daniel E. Larcombe Elena Shekhova Mihai G. Netea Gordon D. Brown Lars Erwig Neil A. R. Gow Alistair J. P. Brown |
| spellingShingle |
Arnab Pradhan Gabriela M. Avelar Judith M. Bain Delma Childers Chloe Pelletier Daniel E. Larcombe Elena Shekhova Mihai G. Netea Gordon D. Brown Lars Erwig Neil A. R. Gow Alistair J. P. Brown Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion Nature Communications |
| author_facet |
Arnab Pradhan Gabriela M. Avelar Judith M. Bain Delma Childers Chloe Pelletier Daniel E. Larcombe Elena Shekhova Mihai G. Netea Gordon D. Brown Lars Erwig Neil A. R. Gow Alistair J. P. Brown |
| author_sort |
Arnab Pradhan |
| title |
Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion |
| title_short |
Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion |
| title_full |
Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion |
| title_fullStr |
Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion |
| title_full_unstemmed |
Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion |
| title_sort |
non-canonical signalling mediates changes in fungal cell wall pamps that drive immune evasion |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2019-11-01 |
| description |
The authors show that the fungal pathogen Candida albicans exploits diverse host-associated signals, including specific nutrients and stresses, to promote immune evasion by masking cell wall β-glucan, a major pathogen-associated molecular pattern. |
| url |
https://doi.org/10.1038/s41467-019-13298-9 |
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