A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of

A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of

Previous findings suggest that copper plays a crucial role in the antimutagenic effect of sodium copper chlorophyllin (SCC). The objective of the current research was to compare the antimutagenic effects of two SCC compounds with different amounts of copper (3.7% and 5.4%, respectively) on the genet...

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Main Authors: Emilio Pimentel, Martha P. Cruces, Stanley Zimmering
Format: Article
Language:English
Published: SAGE Publishing 2013-01-01
Series:Biomarker Insights
Online Access:https://doi.org/10.4137/BMI.S11081
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spelling doaj-bd33dd64f98840188237b21db852c8342020-11-25T03:38:46ZengSAGE PublishingBiomarker Insights1177-27192013-01-01810.4137/BMI.S11081A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of Emilio Pimentel0Martha P. Cruces1Stanley Zimmering2Departamento de Biología, Instituto Nacional de Investigaciones Nucleares (ININ), Carretera México-Toluca S/N, La Marquesa, Ocoyoacac, México CP, México.Departamento de Biología, Instituto Nacional de Investigaciones Nucleares (ININ), Carretera México-Toluca S/N, La Marquesa, Ocoyoacac, México CP, México.Program in Biology, Brown University, Providence, RI, USA.Previous findings suggest that copper plays a crucial role in the antimutagenic effect of sodium copper chlorophyllin (SCC). The objective of the current research was to compare the antimutagenic effects of two SCC compounds with different amounts of copper (3.7% and 5.4%, respectively) on the genetic damage induced by gamma rays in somatic cells of Drosophila . Data indicate that an increase in copper content of 31.5% in SCC-5.4 resulted in a greater inhibition of gamma ray genetic damage of 49% whereas only a 2% inhibition with SCC-3.7 occurred. Of greater interest is the association of SCC with a variety of uses in humans, such as a chemo preventive agent and food supplement. A greater attention to the concentration of copper in the SCC product in use should be required.https://doi.org/10.4137/BMI.S11081
collection DOAJ
language English
format Article
sources DOAJ
author Emilio Pimentel
Martha P. Cruces
Stanley Zimmering
spellingShingle Emilio Pimentel
Martha P. Cruces
Stanley Zimmering
A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of
Biomarker Insights
author_facet Emilio Pimentel
Martha P. Cruces
Stanley Zimmering
author_sort Emilio Pimentel
title A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of
title_short A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of
title_full A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of
title_fullStr A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of
title_full_unstemmed A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of
title_sort further study of the role of copper in regard to the antimutagenic action of sodium copper chlorophyllin (scc) in somatic cells of
publisher SAGE Publishing
series Biomarker Insights
issn 1177-2719
publishDate 2013-01-01
description Previous findings suggest that copper plays a crucial role in the antimutagenic effect of sodium copper chlorophyllin (SCC). The objective of the current research was to compare the antimutagenic effects of two SCC compounds with different amounts of copper (3.7% and 5.4%, respectively) on the genetic damage induced by gamma rays in somatic cells of Drosophila . Data indicate that an increase in copper content of 31.5% in SCC-5.4 resulted in a greater inhibition of gamma ray genetic damage of 49% whereas only a 2% inhibition with SCC-3.7 occurred. Of greater interest is the association of SCC with a variety of uses in humans, such as a chemo preventive agent and food supplement. A greater attention to the concentration of copper in the SCC product in use should be required.
url https://doi.org/10.4137/BMI.S11081
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