Intraosseous chemotherapy in the treatment of invasive bladder carcinoma

Intraosseous chemotherapy in the treatment of invasive bladder carcinoma

Neoadjuvant chemotherapy (CT) with cisplatin administered intraosseously into the pubic bone in patients with invasive bladder carcinoma (Т2—4N0M0) was most effective in patients with circular involvement of the bladder neck, even in large tumors of 5—7 cm. Out of 4 patients with this site of a tumo...

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Main Authors: S. P. Selivanov, S. N. Isayeva, T. A. Kovalik, A. V. Petlin, Ye. A. Kaliyev
Format: Article
Language:Russian
Published: ABV-press 2020-02-01
Series:Onkourologiâ
Online Access:https://oncourology.abvpress.ru/oncur/article/view/1083
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spelling doaj-bd260c2c6325445d8739fb5fefd002992021-07-29T08:41:45ZrusABV-pressOnkourologiâ 1726-97761996-18122020-02-0131333610.17650/1726-9776-2007-3-1-33-36966Intraosseous chemotherapy in the treatment of invasive bladder carcinomaS. P. Selivanov0S. N. Isayeva1T. A. Kovalik2A. V. Petlin3Ye. A. Kaliyev4Treatment-and-Diagnostic Center, TomskTreatment-and-Diagnostic Center, TomskTreatment-and-Diagnostic Center, TomskTreatment-and-Diagnostic Center, TomskTreatment-and-Diagnostic Center, TomskNeoadjuvant chemotherapy (CT) with cisplatin administered intraosseously into the pubic bone in patients with invasive bladder carcinoma (Т2—4N0M0) was most effective in patients with circular involvement of the bladder neck, even in large tumors of 5—7 cm. Out of 4 patients with this site of a tumor, full regression without further treatment was achieved in one patient, transurethral resection was performed in 3 patients with 75% tumor regression. In multiple bladder tumor lesions involving the bladder neck, the degree of regression was not greater than 40%. The therapeutic efficiency of intraosseous CT with cisplatin was 54% with acceptable toxicity.https://oncourology.abvpress.ru/oncur/article/view/1083
collection DOAJ
language Russian
format Article
sources DOAJ
author S. P. Selivanov
S. N. Isayeva
T. A. Kovalik
A. V. Petlin
Ye. A. Kaliyev
spellingShingle S. P. Selivanov
S. N. Isayeva
T. A. Kovalik
A. V. Petlin
Ye. A. Kaliyev
Intraosseous chemotherapy in the treatment of invasive bladder carcinoma
Onkourologiâ
author_facet S. P. Selivanov
S. N. Isayeva
T. A. Kovalik
A. V. Petlin
Ye. A. Kaliyev
author_sort S. P. Selivanov
title Intraosseous chemotherapy in the treatment of invasive bladder carcinoma
title_short Intraosseous chemotherapy in the treatment of invasive bladder carcinoma
title_full Intraosseous chemotherapy in the treatment of invasive bladder carcinoma
title_fullStr Intraosseous chemotherapy in the treatment of invasive bladder carcinoma
title_full_unstemmed Intraosseous chemotherapy in the treatment of invasive bladder carcinoma
title_sort intraosseous chemotherapy in the treatment of invasive bladder carcinoma
publisher ABV-press
series Onkourologiâ
issn 1726-9776
1996-1812
publishDate 2020-02-01
description Neoadjuvant chemotherapy (CT) with cisplatin administered intraosseously into the pubic bone in patients with invasive bladder carcinoma (Т2—4N0M0) was most effective in patients with circular involvement of the bladder neck, even in large tumors of 5—7 cm. Out of 4 patients with this site of a tumor, full regression without further treatment was achieved in one patient, transurethral resection was performed in 3 patients with 75% tumor regression. In multiple bladder tumor lesions involving the bladder neck, the degree of regression was not greater than 40%. The therapeutic efficiency of intraosseous CT with cisplatin was 54% with acceptable toxicity.
url https://oncourology.abvpress.ru/oncur/article/view/1083
work_keys_str_mv AT spselivanov intraosseouschemotherapyinthetreatmentofinvasivebladdercarcinoma
AT snisayeva intraosseouschemotherapyinthetreatmentofinvasivebladdercarcinoma
AT takovalik intraosseouschemotherapyinthetreatmentofinvasivebladdercarcinoma
AT avpetlin intraosseouschemotherapyinthetreatmentofinvasivebladdercarcinoma
AT yeakaliyev intraosseouschemotherapyinthetreatmentofinvasivebladdercarcinoma
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