Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγnull mice engrafted with human peripheral blood mononuclear cells
SUMMARY Animal models mimicking human diseases have been used extensively to study the pathogenesis of autoimmune diseases and the efficacy of potential therapeutics. They are, however, limited with regard to their similarity to the human disease and cannot be used if the antagonist and its cognate...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-01-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/6/1/125 |