Parthenolide Augments the Chemosensitivity of Non-small-Cell Lung Cancer to Cisplatin via the PI3K/AKT Signaling Pathway

Parthenolide Augments the Chemosensitivity of Non-small-Cell Lung Cancer to Cisplatin via the PI3K/AKT Signaling Pathway

The mortality rate of non-small-cell lung cancer (NSCLC) remains high worldwide. Although cisplatin-based chemotherapy may greatly enhance patient prognosis, chemotherapy resistance remains an obstacle to curing patients with NSCLC. Therefore, overcoming drug resistance is the main route to successf...

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Bibliographic Details
Main Authors: Li-Mei Wu, Xiao-Zhong Liao, Yan Zhang, Zi-Rui He, Shi-Qing Nie, Bin Ke, Lin Shi, Jian-Fu Zhao, Wen-Hui Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
PTL
DDP
combination
synergistic effect
NSCLC
PI3K/Akt pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.610097/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.610097/full

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