Apigenin Inhibits IL-31 Cytokine in Human Mast Cell and Mouse Skin Tissues

Apigenin Inhibits IL-31 Cytokine in Human Mast Cell and Mouse Skin Tissues

IL-31 is a recently discovered cytokine that is produced not only in T-cells but also in mast cells. It is strongly implicated to play a key role in inflammatory diseases and in the pathogenesis of itch in atopic dermatitis. Apigenin, a flavonoid of plant origin has numerous biological applications....

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Bibliographic Details
Main Authors: Denis Nchang Che, Byoung Ok Cho, Jae Young Shin, Hyun Ju Kang, Ji-Su Kim, Hyeonhwa Oh, Young-Soo Kim, Seon Il Jang
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Molecules
Subjects:
IL-31
apigenin
mast cells
atopic dermatitis
MAPK
NF-κB
Online Access:https://www.mdpi.com/1420-3049/24/7/1290

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